Thursday September 1, 2011, 16.00 – 17.00 hrs
Anders Ahlbom
Professor of Environmental Medicine
Karolinska Institutet, Stockholm, Sweden
Confounding and effect modification are basic concepts to epidemiologists and are on one level easy to grasp. Yet, they have created confusion and occasionally heated debate for decades. From some perspectives they have rather little in common but on the other hand they are both addressed by multivariable modeling and thus appear in tandem in many analyses. On top of this is the sometimes also heated discussion of biological interaction versus statistical interaction. The purpose of this lecture is to provide a historical perspective to the seemingly never ending discussion about these fundamental concepts and also to provide as clear as possible an explanation of what confounding and effect modification and some related concepts actually are. While the talk will be mainly on concepts and ideas there will be some discussion about methodological approaches as well.














