Human Epigenomics [ESP75]

Detailed information about this course:

Description

Faculty: Jordana Bell, PhD

This course is formerly known as Epigenetics.

This course aims to give an introduction to epigenetics and epigenomic studies of human disease. The course offers an overview of epigenetic mechanisms and their importance during development and over the life course. Different sources of epigenomic variation will be discussed, as well as approaches to characterize epigenomic variability with the use of modern molecular and bioinformatics methods. The course will then focus on epigenomic studies of human disease, to enable participants to interpret the findings in modern epigenetic research and put these into a functional perspective.

A laptop is required for computer exercises during the course.

Objectives

After completing the course, students should be able to:

• Describe epigenetic mechanisms and understand their role during development, over the lifecourse, and in disease.
• Understand the sources of epigenetic variation.
• Perform a basic epigenome-wide association analysis.
• Interpret results and evaluate them in a functional context.
  

Participant profile

Basic science researchers, clinicians with an interest in epigenetic research, and postdoctoral scientists and graduate students in the fields of genetics, molecular biology, bioinformatics, computer science, and other quantitative fields.

Assessment

Attendance