Erasmus Summer Programme Courses

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Case-control Studies [ESP40]

Course highlights

ECTS

0.7

Start date

14 August 2017

End date

18 August 2017

Course days

Monday to Friday (5 mornings)

Course time

From 8:45 till 11:45

Faculty

Prof. Moyses Szklo

Course fee

€ 710

Location

Erasmus MC, Rotterdam NL

Level

Intermediate

Prerequisites

Introductory level epidemiology course work and introductory level biostatistics.

Disciplines

  • Methodology
  • Clinical Epidemiology
  • Clinical Research
  • Epidemiology

Course Materials

Online, download instructions will be sent in August by e-mail.

Recommended books:
Epidemiology: beyond the Basics by M. Szklo and F. Javier Nieto. ISBN: 076374722x. Published: Sudbury, Mass; Jones and Barlett. C2004

Case-Control studies; design, conduct, analysis by James. J. Schlesselman, with contributions by Paul D. Stolley. ISBN: 019502933x Published: New York: Oxford Univ. Press, C1982

Epidemiologic Reviews Volume 16. #1: John Hopkins Univ, C1994

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Description

Faculty: Prof. Moyses Szklo, MD PhD

The course will provide an introduction to the design and analysis of case-control studies. Topics to be covered include case-based case-control, nested case-control and case-cohort designs, selection of cases and controls, the parameter measured by the odds ratio as a function of control selection, matched and unmatched strategies, common biases, and evaluation of additive and multiplicative interaction in case-control studies. These topics will be discussed in the context of the case-control design as a special way to analyze cohort data. In addition, a discussion of adjustment approaches appropriate to case-control data will be covered, including stratified and regression methods. The course will be based on classroom lectures and small group discussions of exercises.

Objectives

- To understand the main case-control study designs and understand the importance of the type of control group to the parameter estimated by the exposure odds ratio;
- To recognize the main problems when drawing inferences from results of case-control studies;
- To learn and apply the main techniques of confounding adjustment and assessment of interactions in case-control studies.

Assessment

Attendance